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Diminished virulence of a sar-/agr- mutant of Staphylococcus aureus in the rabbit model of endocarditis.

Microbial pathogenicity in Staphylococcus aureus is a complex process involving a number of virulence genes that are regulated by global regulatory systems including sar and agr. To evaluate the roles of these two loci in virulence, we constructed sar-/agr- mutants of strains RN6390 and RN450 and co...

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Autors principals: Cheung, A L, Eberhardt, K J, Chung, E, Yeaman, M R, Sullam, P M, Ramos, M, Bayer, A S
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC294579/
https://ncbi.nlm.nih.gov/pubmed/7962526
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