Clumping Factor A Mediates Binding of Staphylococcus aureus to Human Platelets

The direct binding of bacteria to platelets may be an important virulence mechanism in the pathogenesis of infective endocarditis. We have previously described Staphylococcus aureus strain PS12, a Tn551-derived mutant of strain ISP479, with reduced ability to bind human platelets in vitro. When test...

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Main Authors: Siboo, Ian R., Cheung, Ambrose L., Bayer, Arnold S., Sullam, Paul M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC98267/
https://ncbi.nlm.nih.gov/pubmed/11292731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3120-3127.2001
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