Early Detection of Response to Experimental Chemotherapeutic Top216 with [(18)F]FLT and [(18)F]FDG PET in Human Ovary Cancer Xenografts in Mice

BACKGROUND: 3′-deoxy-3′-[(18)F]fluorothymidine ((18)F-FLT) is a tracer used to assess cell proliferation in vivo. The aim of the study was to use (18)F-FLT positron emission tomography (PET) to study treatment responses to a new anti-cancer compound. To do so, we studied early anti-proliferative eff...

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Detalhes bibliográficos
Main Authors: Munk Jensen, Mette, Erichsen, Kamille Dumong, Björkling, Fredrik, Madsen, Jacob, Jensen, Peter Buhl, Højgaard, Liselotte, Sehested, Maxwell, Kjær, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945761/
https://ncbi.nlm.nih.gov/pubmed/20885974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012965
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