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HIV-1 macrophage tropism is determined at multiple levels of the viral replication cycle.

The ability of HIV-1 to infect macrophages is thought to be essential in AIDS pathogenesis. We tested the ability of 19 primary virus isolates to infect monocyte-derived macrophages (MDM) from different donors. Two HIV-1 isolates were able to establish a productive infection in MDM from all donors t...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Fouchier, R A, Brouwer, M, Kootstra, N A, Huisman, H G, Schuitemaker, H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294575/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7962525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117529
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