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HIV-1 macrophage tropism is determined at multiple levels of the viral replication cycle.

The ability of HIV-1 to infect macrophages is thought to be essential in AIDS pathogenesis. We tested the ability of 19 primary virus isolates to infect monocyte-derived macrophages (MDM) from different donors. Two HIV-1 isolates were able to establish a productive infection in MDM from all donors t...

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Bibliographic Details
Main Authors: Fouchier, R A, Brouwer, M, Kootstra, N A, Huisman, H G, Schuitemaker, H
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC294575/
https://ncbi.nlm.nih.gov/pubmed/7962525
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