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NAD(+) Auxotrophy is Bacteriocidal for the Tubercle Bacilli
The human tubercle bacillus Mycobacterium tuberculosis can synthesize NAD(+) using the de novo biosynthesis pathway or the salvage pathway. The salvage pathway of the bovine tubercle bacillus M. bovis was reported defective due to a mutation in the nicotinamidase PncA. This defect prevents nicotinic...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2945688/ https://ncbi.nlm.nih.gov/pubmed/20199601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2010.07099.x |
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