Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana

Human DNA polymerase η (HsPolη) plays an important role in translesion synthesis (TLS), which allows for replication past DNA damage such as UV-induced cis-syn cyclobutane pyrimidine dimers (CPDs). Here, we characterized ApPolη from the thermophilic worm Alvinella pompejana, which inhabits deep-sea...

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Detalhes bibliográficos
Main Authors: Kashiwagi, Sayo, Kuraoka, Isao, Fujiwara, Yoshie, Hitomi, Kenichi, Cheng, Quen J., Fuss, Jill O., Shin, David S., Masutani, Chikahide, Tainer, John A., Hanaoka, Fumio, Iwai, Shigenori
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945680/
https://ncbi.nlm.nih.gov/pubmed/20936172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/701472
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