High Affinity of Interaction between Superantigen and T Cell Receptor Vβ Molecules Induces a High Level and Prolonged Expansion of Superantigen-reactive CD4(+) T Cells

In mice implanted with an osmotic pump filled with the superantigen (SAG) staphylococcal enterotoxin A (SEA), the Vβ3(+)CD4(+) T cells exhibited a high level of expansion whereas the Vβ11(+)CD4(+) T cells exhibited a mild level of expansion. In contrast, in mice implanted with an osmotic pump filled...

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Detaylı Bibliyografya
Asıl Yazarlar: Omoe, Katsuhiko, Nunomura, Wataru, Kato, Hidehito, Li, Zhong-Juan, Igarashi, Osamu, Araake, Minako, Sano, Keigo, Ono, Hisaya K., Abe, Yohei, Hu, Dong-Liang, Nakane, Akio, Kiyono, Hiroshi, Takakuwa, Yuichi, Shinagawa, Kunihiro, Uchiyama, Takehiko, Imanishi, Ken'ichi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2010
Konular:
Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945535/
https://ncbi.nlm.nih.gov/pubmed/20663890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.140871
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