A Mutant of Staphylococcal Enterotoxin C Devoid of Bacterial Superantigenic Activity Elicits a Th2 Immune Response for Protection against Staphylococcus aureus Infection

Staphylococcal enterotoxin C (SEC), a bacterial superantigenic exotoxin, is commonly produced by invasive Staphylococcus aureus isolates, especially methicillin-resistant strains and isolates from animal diseases. We constructed and expressed a nontoxic mutant SEC (mSEC) and investigated whether imm...

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Detalhes bibliográficos
Main Authors: Hu, Dong-Liang, Cui, Jing-Chun, Omoe, Katsuhiko, Sashinami, Hiroshi, Yokomizo, Yuichi, Shinagawa, Kunihiro, Nakane, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538976/
https://ncbi.nlm.nih.gov/pubmed/15618152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.174-180.2005
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