A Mutant of Staphylococcal Enterotoxin C Devoid of Bacterial Superantigenic Activity Elicits a Th2 Immune Response for Protection against Staphylococcus aureus Infection

Staphylococcal enterotoxin C (SEC), a bacterial superantigenic exotoxin, is commonly produced by invasive Staphylococcus aureus isolates, especially methicillin-resistant strains and isolates from animal diseases. We constructed and expressed a nontoxic mutant SEC (mSEC) and investigated whether imm...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Hu, Dong-Liang, Cui, Jing-Chun, Omoe, Katsuhiko, Sashinami, Hiroshi, Yokomizo, Yuichi, Shinagawa, Kunihiro, Nakane, Akio
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2005
Fag:	Microbial Immunity and Vaccines
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15618152/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.73.1.174-180.2005
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