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Mouse Atonal Homolog 1 Directs Intestinal Progenitors to Secretory Cell Rather than Absorptive Cell Fate

The Notch-regulated transcription factor mouse atonal homolog 1 (Math1) is required for the development of intestinal secretory cells, as demonstrated by the loss of goblet, endocrine and Paneth cell types in null mice. However, it was unknown whether Math1 is sufficient to induce the program of sec...

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Autori principali: VanDussen, Kelli L., Samuelson, Linda C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945455/
https://ncbi.nlm.nih.gov/pubmed/20691176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.07.026
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