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A Single-Strand Specific Lesion Drives MMS-Induced Hypermutability at a Double-Strand Break in Yeast
Localized hypermutability (LHM) can be important in evolution, immunity, and genetic diseases. We previously reported that single-strand DNA (ssDNA) can be an important source of damage-induced LHM in yeast. Here, we establish that the generation of LHM by methyl methanesulfonate (MMS) during repair...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2945237/ https://ncbi.nlm.nih.gov/pubmed/20663718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.06.005 |
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