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Ligand-independent TLR signals generated by ectopic overexpression of MyD88 generate local and systemic anti-tumor immunity

Although critical for initiating and regulating immune responses, the therapeutic use of individual cytokines as anti-cancer immunotherapeutic agents has achieved only modest clinical success. Consequently, many current strategies have focused on the use of specific immunotherapeutic agonists that e...

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Bibliografiske detaljer
Main Authors: Hartman, Zachary C., Osada, Takuya, Glass, Oliver, Yang, Xiao Y., Lei, Gang-jun, Lyerly, H. Kim, Clay, Timothy M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945227/
https://ncbi.nlm.nih.gov/pubmed/20823152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0905
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