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Discovering Tumor Suppressor Genes Through Genome-Wide Copy Number Analysis

Classical tumor suppressor gene discovery has largely involved linkage analysis and loss-of-heterozygosity (LOH) screens, followed by detailed mapping of relatively large chromosomal regions. Subsequent efforts made use of genome-wide PCR-based methods to detect rare homozygous deletions. More recen...

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Dettagli Bibliografici
Autori principali: Rothenberg, S. Michael, Settleman, Jeff
Natura: Artigo
Lingua:Inglês
Pubblicazione: Bentham Science Publishers Ltd 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944996/
https://ncbi.nlm.nih.gov/pubmed/21286308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920210791616734
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