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Potentiation by granulocyte macrophage colony-stimulating factor of lipopolysaccharide toxicity in mice.

GM-CSF is known to prime leukocytes for inflammatory stimuli in vitro. The objective of this study was to investigate the role of GM-CSF in vivo in a systemic inflammatory reaction syndrome. The results demonstrate a potentiation of LPS toxicity by GM-CSF in a mortality model as well as in a septic...

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Pubblicato in:J Clin Invest
Autori principali: Tiegs, G, Barsig, J, Matiba, B, Uhlig, S, Wendel, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1994
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294498/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8201000/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117274
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