Potentiation by granulocyte macrophage colony-stimulating factor of lipopolysaccharide toxicity in mice.
GM-CSF is known to prime leukocytes for inflammatory stimuli in vitro. The objective of this study was to investigate the role of GM-CSF in vivo in a systemic inflammatory reaction syndrome. The results demonstrate a potentiation of LPS toxicity by GM-CSF in a mortality model as well as in a septic...
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| Udgivet i: | J Clin Invest |
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| Principais autores: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1994
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294498/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8201000/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117274 |
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