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Abrogation of E-Cadherin-Mediated Cellular Aggregation Allows Proliferation of Pluripotent Mouse Embryonic Stem Cells in Shake Flask Bioreactors

BACKGROUND: A fundamental requirement for the exploitation of embryonic stem (ES) cells in regenerative medicine is the ability to reproducibly derive sufficient numbers of cells of a consistent quality in a cost-effective manner. However, undifferentiated ES cells are not ideally suited to suspensi...

詳細記述

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書誌詳細
主要な著者: Mohamet, Lisa, Lea, Michelle L., Ward, Christopher M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944850/
https://ncbi.nlm.nih.gov/pubmed/20886069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012921
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