Ebolavirus Is Internalized into Host Cells via Macropinocytosis in a Viral Glycoprotein-Dependent Manner

Ebolavirus (EBOV) is an enveloped, single-stranded, negative-sense RNA virus that causes severe hemorrhagic fever with mortality rates of up to 90% in humans and nonhuman primates. Previous studies suggest roles for clathrin- or caveolae-mediated endocytosis in EBOV entry; however, ebolavirus virion...

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Autors principals: Nanbo, Asuka, Imai, Masaki, Watanabe, Shinji, Noda, Takeshi, Takahashi, Kei, Neumann, Gabriele, Halfmann, Peter, Kawaoka, Yoshihiro
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944813/
https://ncbi.nlm.nih.gov/pubmed/20886108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001121
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