A Major Determinant of Cyclophilin Dependence and Cyclosporine Susceptibility of Hepatitis C Virus Identified by a Genetic Approach

Since the advent of genome-wide small interfering RNA screening, large numbers of cellular cofactors important for viral infection have been discovered at a rapid pace, but the viral targets and the mechanism of action for many of these cofactors remain undefined. One such cofactor is cyclophilin A...

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Hauptverfasser: Yang, Feng, Robotham, Jason M., Grise, Henry, Frausto, Stephen, Madan, Vanesa, Zayas, Margarita, Bartenschlager, Ralf, Robinson, Margaret, Greenstein, Andrew E., Nag, Anita, Logan, Timothy M., Bienkiewicz, Ewa, Tang, Hengli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944805/
https://ncbi.nlm.nih.gov/pubmed/20886100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001118
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