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Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors
The precise mechanisms whereby anti-angiogenesis therapy blocks tumour growth or causes vascular toxicity are unknown. We propose that endothelial cells establish a vascular niche that promotes tumour growth and tissue repair not only by delivering nutrients and O(2) but also through an ‘angiocrine’...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944775/ https://ncbi.nlm.nih.gov/pubmed/20094048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2791 |
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