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Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors

The precise mechanisms whereby anti-angiogenesis therapy blocks tumour growth or causes vascular toxicity are unknown. We propose that endothelial cells establish a vascular niche that promotes tumour growth and tissue repair not only by delivering nutrients and O(2) but also through an ‘angiocrine’...

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Autors principals: Butler, Jason M., Kobayashi, Hideki, Rafii, Shahin
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944775/
https://ncbi.nlm.nih.gov/pubmed/20094048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2791
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