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Targeting botulinum neurotoxin persistence by the ubiquitin-proteasome system

Botulinum neurotoxins (BoNTs) are the most potent natural toxins known. The effects of BoNT serotype A (BoNT/A) can last several months, whereas the effects of BoNT serotype E (BoNT/E), which shares the same synaptic target, synaptosomal-associated protein 25 (SNAP25), last only several weeks. The l...

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Bibliografiske detaljer
Main Authors: Tsai, Yien Che, Maditz, Rhyan, Kuo, Chueh-ling, Fishman, Paul S., Shoemaker, Charles B., Oyler, George A., Weissman, Allan M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944746/
https://ncbi.nlm.nih.gov/pubmed/20823219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008302107
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