In vivo effects of IgA and IgG2a anti-CD3 isotype switch variants.

Side effects after the first administration of OKT3, a murine anti-CD3 monoclonal antibody (mAb) of the IgG2a class, are largely attributed to the release of cytokines as a result of T cell activation caused by interaction with Fc receptors (FcR) on human monocytes. As human monocytes possess FcR fo...

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Autors principals: Parlevliet, K J, ten Berge, I J, Yong, S L, Surachno, J, Wilmink, J M, Schellekens, P T
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC294472/
https://ncbi.nlm.nih.gov/pubmed/8200988
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