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Mitochondrial aldehyde dehydrogenase mediates vasodilator responses of glyceryl trinitrate and sodium nitrite in the pulmonary vascular bed of the rat

It has been reported that mitochondrial aldehyde dehydrogenase (ALDH2) catalyzes the formation of glyceryl dinitrate and inorganic nitrite from glyceryl trinitrate (GTN), leading to an increase in cGMP and vasodilation in the coronary and systemic vascular beds. However, the role of nitric oxide (NO...

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Xehetasun bibliografikoak
Egile Nagusiak: Badejo, Adeleke M., Hodnette, Chris, Dhaliwal, Jasdeep S., Casey, David B., Pankey, Edward, Murthy, Subramanyam N., Nossaman, Bobby D., Hyman, Albert L., Kadowitz, Philip J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944483/
https://ncbi.nlm.nih.gov/pubmed/20543077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00959.2009
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