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Nerve-released acetylcholine contracts urinary bladder smooth muscle by inducing action potentials independently of IP(3)-mediated calcium release

Nerve-released ACh is the main stimulus for contraction of urinary bladder smooth muscle (UBSM). Here, the mechanisms by which ACh contracts UBSM are explored by determining Ca(2+) and electrical signals induced by nerve-released ACh. Photolysis of caged inositol 1,4,5-trisphosphate (IP(3)) evoked C...

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Detalhes bibliográficos
Main Authors: Nausch, Bernhard, Heppner, Thomas J., Nelson, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944423/
https://ncbi.nlm.nih.gov/pubmed/20573989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00180.2010
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