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Nerve-evoked purinergic signalling suppresses action potentials, Ca(2+) flashes and contractility evoked by muscarinic receptor activation in mouse urinary bladder smooth muscle

Contraction of urinary bladder smooth muscle (UBSM) is caused by the release of ATP and ACh from parasympathetic nerves. Although both purinergic and muscarinic pathways are important to contraction, their relative contributions and signalling mechanisms are not well understood. Here, the contributi...

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Bibliographic Details
Main Authors: Heppner, Thomas J, Werner, Matthias E, Nausch, Bernhard, Vial, Catherine, Evans, Richard J, Nelson, Mark T
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790264/
https://ncbi.nlm.nih.gov/pubmed/19736301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.178806
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