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Increased cyclooxygenase-2 expression and prostaglandin E(2) production in pressurized renal medullary interstitial cells

Renal medullary interstitial cells (RMICs) are subjected to osmotic, inflammatory, and mechanical stress as a result of ureteral obstruction, which may influence the expression and activity of cyclooxygenase type 2 (COX-2). Inflammatory stress strongly induces COX-2 in RMICs. To explore the direct e...

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Detalhes bibliográficos
Main Authors: Carlsen, Inge, Donohue, Kaitlin E., Jensen, Anja M., Selzer, Angela L., Chen, Jie, Poppas, Dix P., Felsen, Diane, Frøkiær, Jørgen, Nørregaard, Rikke
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944419/
https://ncbi.nlm.nih.gov/pubmed/20610829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00544.2009
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