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Interplay between Secondary and Tertiary Structure Formation in Protein Folding Cooperativity

[Image: see text] Protein folding cooperativity is defined by the nature of the finite-size thermodynamic transition exhibited upon folding: two-state transitions show a free-energy barrier between the folded and unfolded ensembles, while downhill folding is barrierless. A microcanonical analysis, w...

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Autori principali: Bereau, Tristan, Bachmann, Michael, Deserno, Markus
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2010
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944381/
https://ncbi.nlm.nih.gov/pubmed/20822175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja105206w
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