Vasoconstriction resulting from dynamic membrane trafficking of TRPM4 in vascular smooth muscle cells

The melastatin (M) transient receptor potential (TRP) channel TRPM4 mediates pressure and protein kinase C (PKC)-induced smooth muscle cell depolarization and vasoconstriction of cerebral arteries. We hypothesized that PKC causes vasoconstriction by stimulating translocation of TRPM4 to the plasma m...

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Autori principali: Crnich, Rachael, Amberg, Gregory C., Leo, M. Dennis, Gonzales, Albert L., Tamkun, Michael M., Jaggar, Jonathan H., Earley, Scott
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2010
Soggetti:
Vascular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944317/
https://ncbi.nlm.nih.gov/pubmed/20610768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00101.2010
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