Multiple sites in the N-terminal half of simian immunodeficiency virus capsid protein contribute to evasion from rhesus monkey TRIM5α-mediated restriction

BACKGROUND: We previously reported that cynomolgus monkey (CM) TRIM5α could restrict human immunodeficiency virus type 2 (HIV-2) strains carrying a proline at the 120(th )position of the capsid protein (CA), but it failed to restrict those with a glutamine or an alanine. In contrast, rhesus monkey (...

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Bibliographic Details
Main Authors: Kono, Ken, Song, Haihan, Yokoyama, Masaru, Sato, Hironori, Shioda, Tatsuo, Nakayama, Emi E
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944288/
https://ncbi.nlm.nih.gov/pubmed/20825647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-72
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