A Single Amino Acid of the Human Immunodeficiency Virus Type 2 Capsid Affects Its Replication in the Presence of Cynomolgus Monkey and Human TRIM5αs

Human immunodeficiency virus type 2 (HIV-2) strains vary widely in their abilities to grow in Old World monkey (OWM) cells such as those of cynomolgus monkeys (CM). We evaluated eight HIV-2 isolates for their sensitivities to CM TRIM5α, an anti-HIV factor in OWM cells. We found that different HIV-2...

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Detalhes bibliográficos
Main Authors: Song, Haihan, Nakayama, Emi E., Yokoyama, Masaru, Sato, Hironori, Levy, Jay A., Shioda, Tatsuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933286/
https://ncbi.nlm.nih.gov/pubmed/17475650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00406-07
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