PGF(2α)-F-prostanoid receptor signalling via ADAMTS1 modulates epithelial cell invasion and endothelial cell function in endometrial cancer

BACKGROUND: An increase in cancer cell invasion and microvascular density is associated with a poorer prognosis for patients with endometrial cancer. In endometrial adenocarcinoma F-prostanoid (FP) receptor expression is elevated, along with its ligand prostaglandin (PG)F(2α), where it regulates exp...

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Autori principali: Keightley, Margaret C, Sales, Kurt J, Jabbour, Henry N
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944181/
https://ncbi.nlm.nih.gov/pubmed/20840749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-488
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