Interleukin-11 in Endometrial Adenocarcinoma Is Regulated by Prostaglandin F(2α)-F-Prostanoid Receptor Interaction via the Calcium-Calcineurin-Nuclear Factor of Activated T Cells Pathway and Negatively Regulated by the Regulator of Calcineurin-1

Interleukin-11 (IL-11) up-regulates the proliferative and invasive capacity of many cancers. Coexpression of glycoprotein 130 (GP130) and IL-11 receptor α (IL-11Rα) is necessary for high-affinity binding of IL-11 to IL-11Rα. This study investigated the expression of IL-11 and role of prostaglandin F...

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Detalhes bibliográficos
Main Authors: Sales, Kurt J., Grant, Vivien, Cook, Ian H., Maldonado-Pérez, David, Anderson, Richard A., Williams, Alistair R.W., Jabbour, Henry N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797902/
https://ncbi.nlm.nih.gov/pubmed/20008143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090403
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