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Dynamin GTPase regulation is altered by PH domain mutations found in centronuclear myopathy patients

The large GTPase dynamin has an important membrane scission function in receptor-mediated endocytosis and other cellular processes. Self-assembly on phosphoinositide-containing membranes stimulates dynamin GTPase activity, which is crucial for its function. Although the pleckstrin-homology (PH) doma...

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Hlavní autoři: Kenniston, Jon A, Lemmon, Mark A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944063/
https://ncbi.nlm.nih.gov/pubmed/20700106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.187
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