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Dynamin GTPase regulation is altered by PH domain mutations found in centronuclear myopathy patients
The large GTPase dynamin has an important membrane scission function in receptor-mediated endocytosis and other cellular processes. Self-assembly on phosphoinositide-containing membranes stimulates dynamin GTPase activity, which is crucial for its function. Although the pleckstrin-homology (PH) doma...
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Hlavní autoři: | , |
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Médium: | Artigo |
Jazyk: | Inglês |
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Nature Publishing Group
2010
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On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944063/ https://ncbi.nlm.nih.gov/pubmed/20700106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.187 |
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