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Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

Maternal care influences hypothalamic-pituitary-adrenal (HPA) function in the rat through epigenetic programming of glucocorticoid receptor expression. In humans, childhood abuse alters HPA stress responses and increases the risk of suicide. We examined epigenetic differences in a neuron-specific gl...

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Bibliografski detalji
Glavni autori: McGowan, Patrick O, Sasaki, Aya, D’Alessio, Ana C, Dymov, Sergiy, Labonté, Benoit, Szyf, Moshe, Turecki, Gustavo, Meaney, Michael J
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944040/
https://ncbi.nlm.nih.gov/pubmed/19234457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2270
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