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Needle-shaped polymeric particles induce transient disruption of cell membranes

Nano- and microparticles of various shapes have recently been introduced for various drug-delivery applications. Shape of particles has been shown to have an impact on various processes including circulation, vascular adhesion and phagocytosis. Here, we assess the role of particle geometry and surfa...

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Autors principals: Doshi, Nishit, Mitragotri, Samir
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943891/
https://ncbi.nlm.nih.gov/pubmed/20504803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2010.0134.focus
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