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Needle-shaped polymeric particles induce transient disruption of cell membranes

Nano- and microparticles of various shapes have recently been introduced for various drug-delivery applications. Shape of particles has been shown to have an impact on various processes including circulation, vascular adhesion and phagocytosis. Here, we assess the role of particle geometry and surfa...

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Bibliographic Details
Main Authors: Doshi, Nishit, Mitragotri, Samir
Format: Artigo
Language:Inglês
Published: The Royal Society 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943891/
https://ncbi.nlm.nih.gov/pubmed/20504803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2010.0134.focus
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