The Effects of Cardiopulmonary Bypass on Endothelin-1-induced Contraction and Signaling in Human Skeletal Muscle Microcirculation

BACKGROUND: We investigated the effects of cardiopulmonary bypass (CPB) on the contractile response of human peripheral microvasculature to endothelin-1 (ET-1), examined the role of specific ET receptors and protein kinase C-alpha (PKC-α), and analyzed ET-1-related gene/protein expression in this re...

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Hauptverfasser: Feng, Jun, Chu, Louis M, Robich, Michael P, Clements, Richard T, Khabbaz, Kamal R, Hagberg, Robert, Liu, Yuhong, Osipov, Robert M, Sellke, Frank W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943858/
https://ncbi.nlm.nih.gov/pubmed/20837906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.928226
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