DECREASED CONTRACTILE RESPONSE TO ENDOTHELIN-1 OF PERIPHERAL MICROVASCULATURE FROM DIABETIC PATIENTS

OBJECTIVES: We compared the contractile responses to ET-1, with and without the inhibition of ET-A receptors and protein kinase C-alpha (PKC-α) in the human peripheral microvasculature of diabetic and case-matched non-diabetic patients. METHODS: Chest wall skeletal muscle was harvested from patients...

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Main Authors: Feng, Jun, Liu, Yuhong, Khabbaz, Kamal R., Hagberg, Robert, Robich, Michael P., Clements, Richard T., Bianchi, Cesario, Sellke, Frank W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000877/
https://ncbi.nlm.nih.gov/pubmed/20727565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2010.07.003
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