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Intramuscular AAV delivery of NT-3 alters synaptic transmission to motoneurons in adult rats

We examined whether elevating levels of neurotrophin-3 (NT-3) in the spinal cord and dorsal root ganglion (DRG) would alter connections made by muscle spindle afferent fibers on motoneurons. Adeno-associated virus (AAV) serotypes AAV1, AAV2 and AAV5, selected for their tropism profile, were engineer...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Petruska, Jeffrey C., Kitay, Brandon, Boyce, Vanessa S., Kaspar, Brian, Pearse, Damien, Gage, Fred H., Mendell, Lorne M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943849/
https://ncbi.nlm.nih.gov/pubmed/20849530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2010.07392.x
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