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Intramuscular AAV delivery of NT-3 alters synaptic transmission to motoneurons in adult rats
We examined whether elevating levels of neurotrophin-3 (NT-3) in the spinal cord and dorsal root ganglion (DRG) would alter connections made by muscle spindle afferent fibers on motoneurons. Adeno-associated virus (AAV) serotypes AAV1, AAV2 and AAV5, selected for their tropism profile, were engineer...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943849/ https://ncbi.nlm.nih.gov/pubmed/20849530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2010.07392.x |
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