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Visualization of the unfolded protein response in primary tumors reveals unique microenvironments that reflect metabolic variations and predict for tumor growth

Cancer cells exist in harsh microenvironments which are governed by various factors including hypoxia and nutrient deprivation. These microenvironmental stressors activate signaling pathways that affect a cancer cell’s survival. While others have previously measured microenvironmental stressors in t...

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Detalhes bibliográficos
Main Authors: Spiotto, Michael T., Banh, Alice, Papandreou, Ioanna, Cao, Hongbin, Galvez, Michael, Gurtner, Geoffrey, Denko, Nicholas C., Le, Quynh Thu, Koong, Albert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943832/
https://ncbi.nlm.nih.gov/pubmed/20028872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2747
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