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Discordance of MLL-rearranged (MLL-R) infant acute lymphoblastic leukemia in monozygotic twins with spontaneous clearance of preleukemic clone in unaffected twin

Concordance of MLL-rearranged acute leukemia in infant monozygotic twins is thought to be 100% with a very short latency period, suggesting that either the MLL fusion itself is sufficient to cause leukemia or that it promotes the rapid acquisition of additional oncogenic events that result in overt...

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Détails bibliographiques
Auteurs principaux: Chuk, Meredith K., McIntyre, Emily, Small, Donald, Brown, Patrick
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943757/
https://ncbi.nlm.nih.gov/pubmed/19411627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-202259
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