Discordance of MLL-rearranged (MLL-R) infant acute lymphoblastic leukemia in monozygotic twins with spontaneous clearance of preleukemic clone in unaffected twin

Concordance of MLL-rearranged acute leukemia in infant monozygotic twins is thought to be 100% with a very short latency period, suggesting that either the MLL fusion itself is sufficient to cause leukemia or that it promotes the rapid acquisition of additional oncogenic events that result in overt...

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Detalhes bibliográficos
Main Authors: Chuk, Meredith K., McIntyre, Emily, Small, Donald, Brown, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943757/
https://ncbi.nlm.nih.gov/pubmed/19411627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-202259
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