OTX2 is critical for the maintenance and progression of classic medulloblastoma

OTX2 is a developmentally regulated transcription factor that plays important roles in early morphogenesis of the central nervous system. We previously identified OTX2 amplification and overexpression in medulloblastoma cell lines. However, the nature and frequency of OTX2 genetic alterations have n...

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Autori principali: Adamson, David C., Shi, Qun, Wortham, Matthew, Northcott, Paul A., Di, Chunhui, Duncan, Christopher G., Li, Jianjun, McLendon, Roger E., Bigner, Darell D., Taylor, Michael D., Yan, Hai
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943736/
https://ncbi.nlm.nih.gov/pubmed/20028867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2331
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