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Pushing the limits of what is achievable in protein–DNA docking: benchmarking HADDOCK’s performance

The intrinsic flexibility of DNA and the difficulty of identifying its interaction surface have long been challenges that prevented the development of efficient protein–DNA docking methods. We have demonstrated the ability our flexible data-driven docking method HADDOCK to deal with these before, by...

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Hlavní autoři: van Dijk, Marc, Bonvin, Alexandre M. J. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943626/
https://ncbi.nlm.nih.gov/pubmed/20466807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq222
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