Requirements for catalysis in the Cre recombinase active site

Members of the tyrosine recombinase (YR) family of site-specific recombinases catalyze DNA rearrangements using phosphoryl transfer chemistry that is identical to that used by the type IB topoisomerases (TopIBs). To better understand the requirements for YR catalysis and the relationship between the...

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Bibliographic Details
Main Authors: Gibb, Bryan, Gupta, Kushol, Ghosh, Kaushik, Sharp, Robert, Chen, James, Van Duyne, Gregory D.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943603/
https://ncbi.nlm.nih.gov/pubmed/20462863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq384
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