Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

The Nrf2 (nuclear factor E2 p45-related factor 2) transcription factor responds to diverse oxidative and electrophilic environmental stresses by circumventing repression by Keap1, translocating to the nucleus, and activating cytoprotective genes. Nrf2 responses provide protection against chemical ca...

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Autores principales: Malhotra, Deepti, Portales-Casamar, Elodie, Singh, Anju, Srivastava, Siddhartha, Arenillas, David, Happel, Christine, Shyr, Casper, Wakabayashi, Nobunao, Kensler, Thomas W., Wasserman, Wyeth W., Biswal, Shyam
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
Materias:
Genomics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943601/
https://ncbi.nlm.nih.gov/pubmed/20460467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq212
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