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Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis
The Nrf2 (nuclear factor E2 p45-related factor 2) transcription factor responds to diverse oxidative and electrophilic environmental stresses by circumventing repression by Keap1, translocating to the nucleus, and activating cytoprotective genes. Nrf2 responses provide protection against chemical ca...
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主要な著者: | , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Oxford University Press
2010
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943601/ https://ncbi.nlm.nih.gov/pubmed/20460467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq212 |
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