CHARACTERIZATION OF THE N-ACETYL-α-D-GLUCOSAMINYL L-MALATE SYNTHASE (BshA) AND DEACETYLASE (BshB) FUNCTIONS FOR BACILLITHIOL BIOSYNTHESIS IN Bacillus anthracis

Bacillithiol (Cys-GlcN-malate, BSH) has recently been identified as a novel low-molecular-weight thiol in Bacillus anthracis, Staphylococcus aureus, and several other Gram-positive bacteria lacking glutathione and mycothiol. We have now characterized the first two enzymes for the BSH biosynthetic pa...

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Main Authors: Parsonage, Derek, Newton, Gerald L., Holder, Robert C., Wallace, Bret D., Paige, Carleitta, Hamilton, Chris J., Dos Santos, Patricia C., Redinbo, Matthew R., Reid, Sean D., Claiborne, Al
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943542/
https://ncbi.nlm.nih.gov/pubmed/20799687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100698n
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