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A structural and functional analysis of the glycosyltransferase BshA from Staphylococcus aureus: Insights into the reaction mechanism and regulation of bacillithiol production

Bacillithiol is a glucosamine‐derived antioxidant found in several pathogenic Gram‐positive bacteria. The compound is involved in maintaining the appropriate redox state within the cell as well as detoxifying foreign agents like the antibiotic fosfomycin. Bacillithiol is produced via the action of t...

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Bibliographic Details
Published in:Protein Sci
Main Authors: Royer, Christopher J., Cook, Paul D.
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Inc. 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511738/
https://ncbi.nlm.nih.gov/pubmed/30968475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3617
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