NO-Donating Aspirin and Aspirin Partially Inhibit Age-Related Atherosclerosis but Not Radiation-Induced Atherosclerosis in ApoE Null Mice

BACKGROUND: We previously showed that irradiation to the carotid arteries of ApoE(−/−) mice accelerated the development of macrophage-rich, inflammatory atherosclerotic lesions, prone to intra-plaque hemorrhage. In this study we investigated the potential of anti-inflammatory and anti-coagulant inte...

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Main Authors: Hoving, Saske, Heeneman, Sylvia, Gijbels, Marion J. J., te Poele, Johannes A. M., Bolla, Manlio, Pol, Jeffrey F. C., Simons, Michelle Y., Russell, Nicola S., Daemen, Mat J., Stewart, Fiona A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943480/
https://ncbi.nlm.nih.gov/pubmed/20877628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012874
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