Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression

BACKGROUND: The human mitochondrial genome includes only 13 coding genes while nuclear-encoded genes account for 99% of proteins responsible for mitochondrial morphology, redox regulation, and energetics. Mitochondrial pathogenesis occurs in HIV patients and genetically, mitochondrial DNA haplogroup...

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Hlavní autoři: Hendrickson, Sher L., Lautenberger, James A., Chinn, Leslie Wei, Malasky, Michael, Sezgin, Efe, Kingsley, Lawrence A., Goedert, James J., Kirk, Gregory D., Gomperts, Edward D., Buchbinder, Susan P., Troyer, Jennifer L., O'Brien, Stephen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943476/
https://ncbi.nlm.nih.gov/pubmed/20877624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012862
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